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332
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T82763 |
CD33 splicing modulator 1 hydrochloride
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"CD33splicing modulator 1 (Compound 1) hydrochloride 是一种调节CD33/Siglec 3活性的化合物。CD33/Siglec 3 为髓系细胞表面受体,涉及小胶质细胞功能。该化合物通过提升细胞mRNA池中外显子2的剪接变异,展现在神经退行性疾病研究中的应用潜力,包括阿尔茨海默病。" | |||
T62612 | CD33 splicing modulator 1 | ||
CD33 splicing modulator 1 (Compound 1) 是一种 CD33 splicing modulator。CD33/Siglec 3 是一种已知可调节小胶质细胞活性的髓系细胞表面受体。CD33 splicing modulator 1 加强了细胞 mRNA 池中外显子 2 的跳跃。CD33 splicing modulator 1 具有潜力进行包括阿尔茨海默病在内的神经退行性疾病的研究。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-05201 |
Siglec-2/CD22 Protein, Human, Recombinant
CD22 molecule,SIGLEC2, |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.2 kDa and the accession number is P20273-1. | |||
TMPY-05566 |
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)
CD22 molecule,SIGLEC-2,<... |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) is expressed in HEK293 mammalian cells with His tag. The accession number is P20273-1. | |||
TMPY-02034 |
Siglec-2/CD22 Protein, Human, Recombinant (His)
CD22 molecule,SIGLEC2, |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.6 kDa and the accession number is P20273-1. | |||
TMPY-05223 |
Siglec-2/CD22 Protein, Human, Recombinant (His), Biotinylated
SIGLEC-2,CD22 molecule,<... |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.6 kDa and the accession number is P20273-1. | |||
TMPY-05598 |
Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated
SIGLEC2,SIGLEC-2,CD2... |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 103.7 kDa and the accession number is P20273-4. | |||
TMPY-05658 |
Siglec-10 Protein, Human, Recombinant (His)
sialic acid binding Ig like lectin 10,SLG2,PRO940,<... |
Human | HEK293 Cells |
Siglec-10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.5 kDa and the accession number is AAI01726.1. | |||
TMPY-03566 |
Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His)
CD22 molecule,SIGLEC2, |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is Q32M46. | |||
TMPY-05316 |
Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His), Biotinylated
CD22 molecule,SIGLEC-2,<... |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (aa 176-687, His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is Q32M46. | |||
TMPY-04083 |
Siglec-2/CD22 Protein, Mouse, Recombinant (His)
A530093D23,Lyb8,CD22 molecule,Lyb... |
Mouse | HEK293 Cells |
Siglec-2/CD22 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.8 kDa and the accession number is Q3U0M3. | |||
TMPJ-00393 |
Siglec-2/CD22 Protein, Human, Recombinant (hFc)
BL-CAM,SIGLEC2FLJ22814,C... |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 120-150 KDa and the accession number is P20273. | |||
TMPJ-00444 |
Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His)
CD22 antigenMGC130020,B-cell rece... |
Mouse | HEK293 Cells |
Siglec-2/CD22 Protein, Mouse, Recombinant (aa 22-702, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 100-120 KDa and the accession number is AAA02562.1. | |||
TMPJ-00392 |
Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated
T-cell surface antigen Leu-14,CD22 molecul... |
Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 110-130 KDa and the accession number is P20273. | |||
TMPJ-01201 |
Siglec-10 Protein, Mouse, Recombinant (hFc)
MGC126774,SLG2,SiglecG,Siglec... |
Mouse | HEK293 Cells |
Siglec-10 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 110-135 KDa and the accession number is Q80ZE3. | |||
TMPK-01212 |
Siglec-8 Protein, Human, Recombinant (His & Avi), Biotinylated
SIGLEC8,CDw329,SAF2SAF-2... |
Human | HEK293 Cells |
Siglec-8, also known as SAF, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-8 consists of a 347 amino acid (aa) extracellular domain (ECD) with three Ig-like domains.Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. Siglec-8 Protein, Human, Recombinant (His & A... | |||
TMPJ-01361 |
Siglec-8 Protein, Human, Recombinant (mFc)
CD329 antigen,Siglec-8,SAF2SAF- |
Human | HEK293 Cells |
Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Siglec-8 is expressed on eosinophils, basophils, and mast cells, and it shows a binding preference for the carbohydrate 6-O sulfated sLex. At the tissue level, Siglec-8 mRNA was found to be most highly expressed in lung, PBMCs, spleen, and kidney. Mature human Siglec-8 c... | |||
TMPJ-01360 |
Siglec-8 Protein, Human, Recombinant (His)
Siglec8,SAF-2,SAF2SAF-2,... |
Human | HEK293 Cells |
Siglec-8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40-60 KDa and the accession number is Q9NYZ4. | |||
TMPK-01211 |
Siglec-8 Protein, Human, Recombinant (His & Avi)
SIGLEC8,SAF2SAF-2,SAF2,C... |
Human | HEK293 Cells |
Siglec-8, also known as SAF, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-8 consists of a 347 amino acid (aa) extracellular domain (ECD) with three Ig-like domains.Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells. Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. Siglec-8 Protein, Human, Recombinant (His & A... | |||
TMPJ-00370 |
Siglec-10 Protein, Human, Recombinant (hFc & Avi), Biotinylated
siglec-like gene 2,SLG2,sialic ac... |
Human | HEK293 Cells |
Siglec-10 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 100-130 KDa and the accession number is Q96LC7. | |||
TMPJ-01254 |
Siglec-F Protein, Mouse, Recombinant (His)
sialic acid binding Ig like lectin 8,SAF2,SIGLE... |
Mouse | HEK293 Cells |
Siglec 5 to 11 share a high degree of sequence similarity with CD33/Siglec-3 both in their extracellular and intracellular regions. They are collectively referred to as CD33-related Siglecs. One remarkable feature of the CD33-related Siglecs is their differential expression pattern within the hematopoietic system. This fact, together with the presence of two conserved immunoreceptor tyrosine-based inhibition motifs (ITIMs) in their cytoplasmic tails, suggests that CD33-related Siglecs are involv... | |||
TMPJ-01359 |
Siglec-8 Protein, Human, Recombinant (hFc)
SAF2,CD329 antigen,CDw329,Sig... |
Human | HEK293 Cells |
Siglec-8 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 80-100 KDa and the accession number is Q9NYZ4. | |||
TMPK-00366 |
Siglec-10 Protein,Human,Recombinant (aa 17-546, His)
SLG2,SIGLEC10,MGC126774,PRO940 |
Human | HEK293 Cells |
Siglec-10 Protein,Human,Recombinant (aa 17-546, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 59.2 kDa and the accession number is Q96LC7-1. | |||
TMPK-00364 |
Siglec-10 Protein, Human, Recombinant (His & Avi), Biotinylated
SLG2,PRO940,MGC126774,SIGLEC10 |
Human | HEK293 Cells |
Siglec-10 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 61.13 kDa and the accession number is Q96LC7-1. | |||
TMPY-05832 |
Siglec-10 Protein, Human, Recombinant (mFc)
sialic acid binding Ig like lectin 10,SIGLEC-10,SLG... |
Human | HEK293 Cells |
Siglec-10 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 84.60 kDa and the accession number is Q96LC7-1. | |||
TMPY-06862 |
Siglec-7 Protein, Human, Recombinant(aa 1-353, His)
CDw328,Ity,Bcg,AIRM1,p75/AIRM1,SIGLECP... |
Human | HEK293 Cells |
Siglec-7 Protein, Human, Recombinant(aa 1-353, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.4 kDa and the accession number is Q9Y286-1. | |||
TMPK-00363 |
Siglec-10 Protein, Human, Recombinant (His & Avi)
MGC126774,SIGLEC10,PRO940,SLG2 |
Human | HEK293 Cells |
Siglec-10 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 62.64 kDa and the accession number is Q96LC7-1. | |||
TMPY-03549 |
Siglec-5 Protein, Human, Recombinant
OBBP,SIGLEC-5,OBBP2,SIGLEC5,CD170... |
Human | HEK293 Cells |
Siglec-5 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 47.2 kDa and the accession number is O15389. | |||
TMPK-00531 |
Siglec-10 Protein, Cynomolgus, Recombinant (His)
SIGLEC10,PRO940,SLG2,MGC126774 |
Cynomolgus | HEK293 Cells |
Siglec-10 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 59.90 kDa and the accession number is A0A2K5WBX8. | |||
TMPK-00720 |
Siglec-5 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
CD170,CD33 antigen-like 2,OBBP2,SIGLEC... |
Human | HEK293 Cells |
Group B Streptococcus (GBS) causes invasive infections in human newborns. the GBS β-protein attenuates innate immune responses by binding to sialic acid-binding immunoglobulin-like lectin 5 (Siglec-5), an inhibitory receptor on phagocytes.the polymorphism could influence the risk of prematurity among human fetuses of mothers colonized with GBS. This first functionally proven example of a paired receptor system in the Siglec family has multiple implications for regulation of host immunity. | |||
TMPK-00362 |
Siglec-10 Protein, Human, Recombinant (hFc & Avi)
PRO940,SLG2,SIGLEC10,MGC126774 |
Human | HEK293 Cells |
Siglec-10 Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 85.8 kDa and the accession number is Q96LC7-1. | |||
TMPK-00365 |
Siglec-10 Protein, Human, Recombinant (R119A, His & Avi), Biotinylated
PRO940,MGC126774,SLG2,SIGLEC10 |
Human | HEK293 Cells |
Siglec-10 Protein, Human, Recombinant (R119A, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 62.64 kDa and the accession number is Q96LC7-1. | |||
TMPY-02884 |
Siglec-5 Protein, Human, Recombinant (hFc)
OBBP,SIGLEC5,CD33L2,OB-BP2,OBBP |
Human | HEK293 Cells |
Siglec-5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is O15389. | |||
TMPJ-00669 |
Siglec-5 Protein, Human, Recombinant (His & Flag & hFc)
Sialic acid-binding Ig-like lectin 5,OB-BP2,Obesity... |
Human | HEK293 Cells |
Human Siglec-5 are Itype(Igtype) lectins belonging to the Ig superfamily,They are characterized by an N terminal Ig-like V type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2 type domains. SIGLEC5 has also been designated CD170, they are expressed by monocytic or myeloid lineage cells, and also found at high levels in peripheral blood leukocytes, spleen, bone marrow and at lower levels in lymph node, lung, appendix, placenta, pancreas and thymus. SIGLEC5 are... | |||
TMPK-00719 |
Siglec-5 Protein, Human, Recombinant (His & Avi), Biotinylated
CD170,SIGLEC5,OBBP2,CD33 antigen-like ... |
Human | HEK293 Cells |
Siglec-5 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 49.3 kDa and the accession number is O15389. | |||
TMPY-03895 |
Siglec-2/CD22 Protein, Mouse, Recombinant (hFc)
Lyb-8,Lyb8,A530093D23,CD22 molecu... |
Mouse | HEK293 Cells |
Siglec-2/CD22 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 104.3 kDa and the accession number is Q3U0M3. | |||
TMPY-00407 |
Siglec-2/CD22 Protein, Rat, Recombinant (His)
CD22 molecule |
Rat | HEK293 Cells |
Siglec-2/CD22 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.7 kDa and the accession number is A6JA30. | |||
TMPY-03360 |
Siglec-2/CD22 Protein, Rhesus, Recombinant (hFc)
CD22 molecule |
Rhesus | HEK293 Cells |
Siglec-2/CD22 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 102.1 kDa and the accession number is EHH29920.1. | |||
TMPY-00158 |
Siglec-2/CD22 Protein, Rat, Recombinant (hFc)
CD22 molecule |
Rat | HEK293 Cells |
Siglec-2/CD22 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 102 kDa and the accession number is A6JA30. | |||
TMPY-00349 |
Siglec-2/CD22 Protein, Rhesus, Recombinant (His)
CD22 molecule |
Rhesus | HEK293 Cells |
Siglec-2/CD22 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.5 kDa and the accession number is EHH29920.1. | |||
TMPY-04808 |
Siglec-3/CD33 Protein, Mouse, Recombinant
gp67,CD33 molecule,Siglec-3 |
Mouse | HEK293 Cells |
Siglec-3/CD33 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 25.6 kDa and the accession number is Q63994-2. | |||
TMPJ-01187 |
Siglec-E Protein, Mouse, Recombinant (hFc)
SiglecE,Siglec-E |
Mouse | HEK293 Cells |
Siglecs are sialic acid specific I‑type lectins that are characterized by an extracellular domain (ECD) with an N‑terminal Ig‑like V‑set domain followed by varying numbers of Ig‑like C2‑set domains. Mouse Siglec‑E, also known as Myeloid Inhibitory Siglec (MIS), is an 80 ‑ 85 kDa member of the CD33‑related subfamily of Siglecs. Rodent and primate Siglec gene families have significantly diverged, and Siglec‑9 is the most likely human ortholog of mouse Siglec‑E. Siglec‑E is expressed as a heavily N... | |||
TMPY-01442 |
DMBT1 Protein, Human, Recombinant (His)
GP340,deleted in malignant brain tumors 1,muclin |
Human | HEK293 Cells |
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo... | |||
TMPJ-00850 |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Protein T1,suppression of tumorigenicity 2,Ly84,DER... |
Mouse | HEK293 Cells |
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2. | |||
TMPY-00891 |
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
neuropilin 1,VEGF165R,CD304,NP1,Neuropilin-1,NRP,BDCA4 |
Human | HEK293 Cells |
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2. | |||
TMPY-02011 |
CD96 Protein, Human, Recombinant (His)
CD96 molecule,TACTILE |
Human | HEK293 Cells |
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2. | |||
TMPY-04113 |
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI... |
Human | E. coli |
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2. | |||
TMPY-01613 |
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
A630052E07Rik,OSF-2,Osf2,PLF,AI74... |
Mouse | HEK293 Cells |
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2. | |||
TMPY-01717 |
VEGF164 Protein, Mouse, Recombinant
vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子 |
Mouse | Baculovirus Insect Cells |
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2. | |||
TMPY-02096 |
TACI Protein, Human, Recombinant (His)
RYZN,IGAD2,CVID,TACI,TNFRSF14B,CVID2,tumor... |
Human | HEK293 Cells |
TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2. | |||
TMPY-00341 |
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
CEK2,HSFGFR3EX,fibroblast growth factor receptor 3,... |
Human | HEK293 Cells |
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2. | |||
TMPY-02820 |
SDF-1 Protein, Human, Recombinant (isoform a)
SDF1,chemokine (C-X-C motif) ligand 12,IRH,SCYB1 |
Human | E. coli |
The human stromal cell-derived factor-1 (SDF1), also known as CXCL12, is a small (8 kDa) cytokine highly conserved chemotactic cytokine belonging to the large family of CXC chemokines. SDF1 is expressed in two isoforms from a single gene that encodes two splice variants, SDF1α and SDF1β, which are identical except for the four residues present in the C-terminus of SDF1β but absent from SDF1α. The chemokine CXCL12 [stromal cell-derived factor-1 (SDF-1)] binds primarily to CXC receptor 4 (CXCR4; C... | |||
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